Fourth Annual Chicago Supportive Oncology Conference

Treatment update for metastatic pancreatic cancer

Maureen R. Hewitt, MD, and Kenneth Yu, MD

Abramson Cancer Center of the University of Pennsylvania, Philadelphia, PA

The treatment of metastatic pancreatic cancer continues to be a major unresolved health problem and a therapeutic challenge, with a poor median survival averaging 3–6 months. Disappointing response rates to standard single-agent therapy have led to a search for more effective agents. Early study results with gemcitabine indicate a potential survival benefit in these patients, which is illustrated here in a case report of a 75-year-old man with metastatic pancreatic adenocarcinoma who has defied the odds. Chemotherapy with GEMOX (gemcitabine and oxaliplatin) was initiated, and the patient has enjoyed a good quality of life, with long-term disease control (stable disease 21 months after diagnosis).

Commun Oncol 2006;3:428–430   print e-mail full text 92 kb