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Defining targets and protecting normal tissues in inverse-planned IMRT for prostate, head and neck, and gynecologic cancers: a comparative review
Hollings Cancer Center, Charleston, SC
The superior radiation dose distributions achievable with inverse-planned intensity-modulated radiation therapy (IMRT), allowing for unparalleled sparing of normal tissues and the potential for dose escalation, have resulted in its incredible popularity and demand. Inverse planning demands a keen understanding of radiographic anatomy for both tumor and critical structure definitions when making decisions regarding dose prescription and constraints for organs at risk. The most extensive investigational experience with this process has been in the treatment of prostate, head and neck, and gynecologic cancers. This review presents a consolidated collection and comparison of the techniques used in some of the most detailed studies involving IMRT for these commonly treated cancers.
| Commun Oncol 2005;2:299–306 | full text |  178 kb |