Community Oncology

Volume 4, Number 6 (June 2007)

Letter from the Editor

358

 

Riding the Capitol Hill roller coaster

David H. Henry, MD, FACP, Editor

Pennsylvania Hospital, Philadelphia, PA

Erythropoiesis-stimulating agents (ESAs) have been in the news lately, so when our editor traveled to Capitol Hill on behalf of the American Society of Hematology, it came at an opportune moment. He got in actual “face time” with elected officials who promised to question Medicare on the wisdom of new rules proposed on ESAs. It’s a policy that, if enacted, would eliminate use of almost 90% of ESAs in oncology, which is not good news for patients.

full text 43 kb

Community Translations

384

 

Vorinostat in cutaneous T-cell lymphoma

Many community oncologists will see a limited number of cases of cutaneous T-cell lymphoma (CTCL). Primary dermatologists often treat this disease; when it progresses, they seek opinions and treatment from referral centers. But despite the relatively small number of people affected by CTCL, there is research dedicated to therapeutic options. The use of oral vorinostat may represent an important additional treatment for CTCL. This drug enables clinicians to convert it from a progressive to a chronic disease.

 

FROM THE COMMUNITY ONCOLOGIST'S PERSPECTIVE
Treatment options for cutaneous T-cell lymphoma expand

Jay Rhee, MD

Annapolis Oncology Center, Annapolis, MD

 

FROM THE ADMINISTRATOR'S PERSPECTIVE
Vorinostat: pharmacoeconomic issues

Aaron Cumpston, PharmD

West Virginia University Hospitals, Morgantown, WV

full text 99 kb

Controversies in Patient Care

389

 

ESAs: whatever happened to evidence-based medicine?

David H. Henry, MD, FACP

Pennsylvania Hospital, Philadelphia, PA

With new data, new FDA rulings, and news across the media on rebates—some call them kickbacks—paid to oncologists and other specialists, erythropoiesis-stimulating agents are at the white hot center of a debate in medicine. Are these drugs overprescribed by physicians eager to collect cash from pharma? Or are they quality-of-life-saving medications doled out judiciously and appropriately? In a series of articles found in the next few pages, as well as two Having Your Say opinion pieces beginning on page 367, we sort through the controversy.

 

ADVERSE EVENT ALERT
The run-up to the ESA controversy and where we go from here

Kara Gleason, BS, and Charles L. Bennett, MD, PhD, MPP

Feinberg School of Medicine, Northwestern University, Chicago, IL

 

A PHYSICIAN'S POINT OF VIEW
The FDA has spoken: now what?

Ralph V. Boccia, MD, FACP

Georgetown University, Center for Cancer and Blood Disorders, Bethesda, MD

 

A PAYOR'S POINT OF VIEW
How one payer has stimulated a change in ESA therapy

Lee Newcomer, MD

UnitedHealthcare, Minneapolis, MN

 

COMMENTARY FROM THE ADMINISTRATOR'S DESK
If insurers jump the gun on policy, patients and practices suffer

Dawn G. Holcombe, FACMPE, MBA

Supportive Oncology Services, Inc., and Connecticut Oncology Association, South Windsor, CT

abstract full text 118 kb

Nursing Management

404

 

Implementing a multisymptom chemotherapy risk assessment tool in two community oncology practices

Charlotte Hwa, AB, Angela Ricci, Cathy Fortenbaugh, RN, MSN, AOCN®, Jill Fallon, RN, MSN, OCN®, CRNI, CHPN, Robin Johnston, MSN-V, AOCNP, and Nancy Leahy, RN, MSN, CRNP, AOCN®

Pennsylvania Oncology Hematology Associates, Philadelphia, PA; Capital Health System, Trenton, NJ; Eastern Connecticut Hematology and Oncology Associates, Norwich, CT; Albert Einstein Cancer Center, Philadelphia, PA

Chemotherapy patients are at high risk for developing symptoms that can delay or preclude treatment, affect quality of life, and even lead to life-endangering events. The AIM Higher risk assessment tool helps clinicians identify individual patient risks and develop strategies to manage or eliminate chemotherapy-related symptoms before and during treatment. This article discusses using the AIM Higher process for prechemotherapy risk assessment in two community practices and describes how it can improve patient care.

abstract full text 317 kb

Managing Side Effects

411

 

Managing medical complications in patients with brain tumors

Myrna R. Rosenfeld, MD, PhD, and Amy A. Pruitt, MD

Department of Neurology, University of Pennsylvania Medical Center, Philadelphia, PA

Patients with primary and metastatic brain tumors are at risk for several major medical problems throughout their illness. The most common problems are tumor-associated vasogenic edema, seizures, and deep venous thrombosis. In addition to the symptoms caused directly by these disorders, the drugs used to treat them can produce significant adverse effects. Appropriate management of these complications can improve quality of life and minimize hospital admissions.

abstract full text 128 kb

Having Your Say

367

 

Are drug rebates good for oncology?

Brian R. Klepper, PhD

Center for Practical Health Reform, Atlantic Beach, FL

When oncologists accept rebates, they’re in danger of compromising their medical judgment, says one reformer. He challenges clinicians to set things right.

full text 115 kb

369

 

Rebates are not the whole story

Linda D. Bosserman, MD, FACP, and Steve Balalian, MBA, COO

Wilshire Oncology Medical Group, Inc., La Verne, CA

We need balanced payment reform as well as transparency in treatment.

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Letters to the Editor

379

 

Treatment considerations for today’s elderly

Marybeth Nelson, RPA-C

Dana-Farber Cancer Institute. Boston, MA

full text 33 kb

379

 

Minimizing vincristine misadministration

Joanna Maudlin Pangilinan, PharmD, BCOP, John F. Mitchell, PharmD, FASHP, and Catherine Christen, PharmD

University of Michigan Health System, Department of Pharmacy Services, Ann Arbor, MI

full text 45 kb

Brief Communications

398

 

Dose-independent synergistic response with gemcitabine and cisplatin in anthracycline-resistant breast cancer and reversal of resistance to gemcitabine with addition of paclitaxel

Renuka Gupta, MD, Harinder Sawhney, MD, Sudar Cynthia, MD, and Pradeep Chandra, MD

Department of Medicine, Wyckoff Heights Medical Center, Brooklyn, NY

 

COMMENTARY
An instructive case, a difference of opinion

Lee S. Schwartzberg, MD

The West Clinic, Memphis, TN

full text 79 kb

402

 

Primary adenocarcinoma of the sigmoid colon diagnosed by uterine curettage: a case report

Cynthia Ann English, DO, and William R. Robinson, MD

Texas Tech University Health Science Center and Harrington Cancer Center, Amarillo, TX

full text 48 kb

Technology

417

 

How 'tech toys' have helped one doctor run a more efficient practice

John J. Fried

For a New Orleans practice, technology has freed staff members from time-consuming chores, helped educate patients, and cut expenses. In an era of lower reimbursement, that all adds up to a win-win situation.

full text 45 kb

Washington Update

419

 

Debunking the myths of reimbursement, rebates, and oncologists' motives

Steven M. Coplon, MHA

Community Oncology Alliance, Memphis, TN

full text 49 kb

420

 

Cancer bills offer promise, gain momentum

full text 43 kb

© 2007 by Elsevier Inc. All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher.

The opinions expressed herein are those of the authors or advertisers. The authors, editors, and publishers make every effort to ensure that no inaccurate or misleading data, opinion, or statement is published in this journal and that drug names, dosages, and recommendations are accurate. However, readers should confirm all dosage schedules against the manufacturer’s package information data. The Publisher, Editorial Board, and their employees accept no liability whatsoever for the consequences of any inaccurate or misleading data, opinion, or statement.